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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 637339Generated: October 30, 2026

Chlorosulfonyl isocyanate → N-chlorosulfonyl-2-oxindole-1-carboxamide

https://huagongshe.com/reaction/637339

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorosulfonyl isocyanateHCID 70918—
ReactantOxindoleHCID 321710—
Reactant2-Oxindole-1-carboxamideHCID 11517274—
ProductN-chlorosulfonyl-2-oxindole-1-carboxamideHCID 13854225—

Reaction Steps

In the second method for preparing the 2-oxindole-1-carboxamide compounds of the formula II, a 2-oxindole of the formula VI is reacted with chlorosulfonyl isocyanate to give the intermediate N-chlorosulfonyl-2-oxindole-1-carboxamide of formula VII, followed by removal of the chlorosulfonyl group by hydrolysis, viz., ##STR10##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04556672
Source datasetuspto-grants-1985_12
ORD IDord-38c75f3a41f843eab86c02b4a529561a
Source noteuspto-grants-1985_12