HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 13647623, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Chlorosulfonyl isocyanate | HCID 70918 | — |
| Reactant | 6-Fluoro-1,3-dihydro-5-methyl-2H-indol-2-one | HCID 13565669 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 13647623 | HCID 13647623 | — |
Reaction Steps
Following the procedure of Example 17, the title compound was prepared from 6-fluoro-5-methyl-2-oxindole (1.0 g, 6.0 mmole) and chlorosulfonyl isocyanate (1.03 g, 7.3 mmole) in toluene (30 ml). Water (5 ml) was used for the hydrolysis step. Yield=0.58 g, 46%, m.p. 200°-203° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04556672 |
| Source dataset | uspto-grants-1985_12 |
| ORD ID | ord-ab2cb139b0c042ce90010eb5102ee8e7 |
| Source note | uspto-grants-1985_12 |