HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 5,6-Dimethoxy-2-oxindole-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Chlorosulfonyl isocyanate | HCID 70918 | — |
| Reactant | 5,6-Dimethoxyindolin-2-one | HCID 222993 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 5,6-Dimethoxy-2-oxindole-1-carboxamide | HCID 13647634 | — |
Reaction Steps
Following the procedure of Example 24, the title compound was prepared from 5,6-dimethoxy-2-oxindole (8.0 g, 0.042 mole), chlorosulfonyl isocyanate (7.08 g, 0.05 mole) and acetonitrile (75 ml). The crude product obtained upon evaporation of the ethyl acetate extract was recrystallized from acetonitrile/acetic acid (1:1). Yield=6.02 g (60%); m.p. 206.5°-209° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04556672 |
| Source dataset | uspto-grants-1985_12 |
| ORD ID | ord-761d4e2d0bf44d76915af218d1429282 |
| Source note | uspto-grants-1985_12 |