反应详情

To a stirred slurry of 20.0 g (0.15 mole) of 2-oxindole in 150 ml of toluene was added 29.6 g (0.19 mole) of cyclohexylcarbonyl isocyanate. The mixture was heated under reflux for ca. 30 minutes and then it was cooled to room temperature. The solid was recovered by filtration and then it was recrystallized from ethanol. This afforded 26.5 g of the title compound as fluffy, colorless crystals, m.p. 144.5°-145.5° C.

1. temperatureThe mixture was heated
2. temperatureunder reflux for ca. 30 minutes
3. filtrationThe solid was recovered by filtration
4. customit was recrystallized from ethanol