HCID 13175276, compound → HCID 13175279, compound

HRID 637379Notes

Reaction equation

HRID 637379 reaction equation
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]([OH:30])([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:16]([CH2:22][CH3:23])[C:17]([O:19][CH2:20][CH3:21])=[O:18])=[CH:11][CH:10]=1)C1C=CC=CC=1>C(O)C.[Pd]>[CH2:22]([CH:16]([C:15]([OH:30])([C:12]1[CH:11]=[CH:10][C:9]([OH:8])=[CH:14][CH:13]=1)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH3:23]

Participants

4

Reactant 1

HCID 13175276HCID 13175276, compound

Product 1

HCID 13175279HCID 13175279, compoundYield 96%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

8.0 g (0.020 mol) of ethyl 3-(p-benzyloxyphenyl)-2-ethyl-3-hydroxy-3-phenylpropionate were hydrogenated in ethanol solution using palladium-charcoal as catalyst to yield 6.0 g (96%) of the product, mp. 46°-53° C.

Sources & evidence

ORD record
ord-888a926f22c244ba9ebbff2566913ecf
Source dataset
uspto-grants-1985_12
Patent number
US04556677

Reaction notes

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