Naphthalene, 1,2-dihydro-4-(4-methoxyphenyl)- → HCID 13408690, compound

HRID 637391Notes

Reaction equation

HRID 637391 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[CH2:12][CH2:11][CH:10]=2)=[CH:5][CH:4]=1>[Pd].C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH:9]2[C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[CH2:12][CH2:11][CH2:10]2)=[CH:7][CH:8]=1

Participants

4

Reactant 1

HCID 12048655Naphthalene, 1,2-dihydro-4-(4-methoxyphenyl)-

Product 1

HCID 13408690HCID 13408690, compoundYield 92.5%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

1-(4-Methoxyphenyl)-3,4-dihydro-naphthalene (12 g., 0.051 mole) was added to a mixture of 10% Pd on carbon catalyst (1.0 g.) and ethanol (250 ml.) and hydrogenated for 4 hours at room temperature and 50 psi of H2. The reaction mixture was then filtered and evaporated under vacuum to an oil, which was used in the next step without further purification (11.2 g., 92.5% yield).

Workup

  1. filtrationThe reaction mixture was then filtered
  2. customevaporated under vacuum to an oil, which
  3. customwas used in the next step without further purification (11.2 g., 92.5% yield)

Sources & evidence

ORD record
ord-1c98b722c3a24f1fb43edbf24c8f7637
Source dataset
uspto-grants-1985_12
Patent number
US04556676

Reaction notes

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