Sulfuric acid magnesium salt (1:1) → HCID 70443455, compound

HRID 637440Notes

Reaction equation

HRID 637440 reaction equation
[Br:1][C:2]1[C:13]2=[C:14]3[N:9]([CH:10]([CH3:15])[CH2:11][CH2:12]2)[CH:8]=[C:7]([C:16]([O-:18])=[O:17])[C:6](=[O:19])[C:5]3=[CH:4][C:3]=1[F:20].[Na+].S([O-])([O-])(=O)=O.[Mg+2:27]>O>[OH2:17].[Br:1][C:2]1[C:13]2=[C:14]3[N:9]([CH:10]([CH3:15])[CH2:11][CH2:12]2)[CH:8]=[C:7]([C:16]([O-:18])=[O:17])[C:6](=[O:19])[C:5]3=[CH:4][C:3]=1[F:20].[Mg+2:27].[Br:1][C:2]1[C:13]2=[C:14]3[N:9]([CH:10]([CH3:15])[CH2:11][CH2:12]2)[CH:8]=[C:7]([C:16]([O-:18])=[O:17])[C:6](=[O:19])[C:5]3=[CH:4][C:3]=1[F:20]

Participants

4

Reactant 2

HCID 24083Sulfuric acid magnesium salt (1:1)HCID 23707684HCID 23707684, compound

Product 1

HCID 70443455HCID 70443455, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A solution of 1.0 g of sodium 8-bromo-6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylate in 30 ml of warm water was stirred with 1 g magnesium sulfate in 20 ml of water and warmed on a steam bath for 15 minutes. Cooling and filtration provided magnesium 8-bromo-6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylate hydrate, m.p. >300° C. Analysis: Calculated for (C14H10BrFNO3)2Mg.H2O; %C, 47.1; %H, 3.0; %N, 3.9; Found: %C, 46.9; %H, 3.2; %N, 3.9.

Workup

  1. temperaturewarmed on a steam bath for 15 minutes
  2. temperatureCooling
  3. filtrationfiltration

Sources & evidence

ORD record
ord-06f1ec7714b348568bbfd66f2874e2dc
Source dataset
uspto-grants-1985_12
Patent number
US04556713

Reaction notes

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