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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 637469Generated: October 29, 2026

Sodium hydride → N,N-Dimethyl-6-(3-thienyl)-11H-pyrido[2,3-b][1,4]benzodiazepine-11-propanamine

https://huagongshe.com/reaction/637469

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium hydrideHCID 24758—
Reactant3-Chloro-N,N-dimethyl-1-propanamineHCID 66960—
Reactant6-(3-thienyl)11H-pyrido[2,3-b][1,4]benzodiazepineHCID 135626370—
ProductN,N-Dimethyl-6-(3-thienyl)-11H-pyrido[2,3-b][1,4]benzodiazepine-11-propanamineHCID 20184008—

Reaction Steps

Following the procedure of Example 23, 6-(3-thienyl)-11H-pyrido[2,3-b][1,4]benzodiazepine is reacted with sodium hydride followed by reaction with 3-dimethylaminopropyl chloride to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04556667
Source datasetuspto-grants-1985_12
ORD IDord-c2fc5ff27c3040509d713d4c77afe804
Source noteuspto-grants-1985_12