HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → {4-[4-(4-Chlorophenyl)butoxy]phenyl}methyl pyridine-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Nicotinoyl chloride | HCID 82604 | — |
| Reactant | HCID 13563047 | HCID 13563047 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | {4-[4-(4-Chlorophenyl)butoxy]phenyl}methyl pyridine-3-carboxylate | HCID 3068164 | — |
Reaction Steps
A mixture of 6.0 g (0.02 mol) of 4-[4-(4-chlorophenyl)butoxy]phenylmethanol and 20.2 g triethylamine is added to 5.3 g(0.03 mol) of hydrochloride of nicotinoyl chloride in 100 ml anhydrous benzene with stirring and the mixture is refluxed for 20 hrs. Thereupon, the solvent is distilled off in vacuo, and water is added.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04556715 |
| Source dataset | uspto-grants-1985_12 |
| ORD ID | ord-3bc43ee0c16041709f411c4d34a58807 |
| Source note | uspto-grants-1985_12 |