反应详情

A solution of 5-(4-aminophenyl)-2(1H)-pyrazinone hydrobromide (2.0 g) in aqueous sodium hydroxide (46 ml, 10%) was treated with benzoyl chloride (1.9 ml) and the mixture was agitated for 2 hours at room temperature. The pale yellow precipitate was collected, washed with water and dried. Recrystallisation from glacial acetic acid gave the title compound (0.9 g), m.p.>300° C.; ν(Nujol mull) 1660 (C=0), 1705 (C=0), 3330 (NH)cm-1.

1. customThe pale yellow precipitate was collected
2. washwashed with water
3. customdried
4. customRecrystallisation from glacial acetic acid