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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 637508Generated: October 30, 2026

Dimethylcarbamoyl Chloride → N,N-Dimethyl-N'-[4-(5-oxo-4,5-dihydropyrazin-2-yl)phenyl]urea

https://huagongshe.com/reaction/637508

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylcarbamoyl ChlorideHCID 6598—
Reactant5-(4-Aminophenyl)-2(1H)-pyrazinone hydrobromideHCID 20208662—
ProductN,N-Dimethyl-N'-[4-(5-oxo-4,5-dihydropyrazin-2-yl)phenyl]ureaHCID 13853583—

Reaction Steps

5-(4-Aminophenyl)-2(1H)-pyrazinone hydrobromide is treated with dimethyl carbamoyl chloride using a procedure similar to that of Example 5 to form 5-[4-(3,3-dimethylureido)phenyl]-2(1H)-pyrazinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04556711
Source datasetuspto-grants-1985_12
ORD IDord-b3da8f37854f4ccca420a187e649de79
Source noteuspto-grants-1985_12