HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → 3,5-Dichloro-2-hydroxybenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 3,5-Dichloro-2-hydroxybenzenesulphonyl chloride | HCID 90078 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3,5-Dichloro-2-hydroxybenzenesulfonamide | HCID 294719 | 71% |
Reaction Steps
A solution of 39.16 g of the product from Example 3 in 100 ml CH2Cl2 was contacted with 250 ml of 28% NH4OH at 5°-8° C. Following removal of CH2Cl2 by a N2 sparge the mixture was acidified to pH 3. Filtration afforded 42.7 g of 61% pure 2-hydroxy-3,5-dichlorobenzenesulfonamide (D) (71% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04556733 |
| Source dataset | uspto-grants-1985_12 |
| ORD ID | ord-e11429a466cf4698accf16afd6405a68 |
| Source note | uspto-grants-1985_12 |