Diethyl Ether → HCID 20257091, compound

Participants

Reaction Steps

Dissolved in 5 ml of dimethylformamide was 2.85 g of 2-{4-(2,3-dihydroxypropoxy)phenylcarbamoyl}ethyl methyl sulfide. To the solution was added 5.00 g of methyl iodide and the mixture was stirred at room temperature for 12 hours. Ether was added to the reaction mixture and the insoluble solid was filtered off, and recrystallized from methanol-ether, giving 4.05 g of 2-{4-(2,3-dihydroxypropoxy)phenylcarbamoyl}ethyldimethylsulfonium iodide (Compound 3) in 94.8% yield, M.P. 113° to 115° C.

Provenance & Evidence