Methyl p-toluenesulfonate → HCID 86740533, compound

Participants

Reaction Steps

Dissolved in 30 ml of methylene chloride was 3.85 g of 2-{4-(3-ethoxy-2-methoxyacetoxypropoxy)phenylcarbamoyl}ethyl methyl sulfide. Thereto was added 5.58 g of methyl p-toluenesulfonate and the mixture was stirred at room temperature for 48 hours. Isopropyl ether was adde to the reaction mixture and the insoluble solid was separated. The solid was purified with acetonitrile-ether, giving 5.30 g of 2-{4-(3-ethoxy-2-methoxyacetoxypropoxy)phenylcarbamoyl}ethyldimethylsulfonium p-toluenesulfonate (Compound 62) in 92.7% yield.

Provenance & Evidence