HCID 53812838, compound → HCID 20257049, compound

HRID 637567Notes

Reaction equation

HRID 637567 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[CH:10][CH:11]=[CH:12][C:13]([O:15][CH3:16])=[O:14])#[N:2]>CO.[Pd]>[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:9][CH2:10][CH2:11][CH2:12][C:13]([O:15][CH3:16])=[O:14])#[N:2]

Participants

4

Reactant 1

HCID 53812838HCID 53812838, compound

Product 1

HCID 20257049HCID 20257049, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Methyl 5-(2-cyanophenyl)-2,4-pentadienoate (15.2 g, 71.4 mmol) was dissolved in methanol (600 ml). After adding palladium black (0.6 g), the solution was subjected to catalytic reduction for 6 hours at room temperature and atmospheric pressure. After the reaction, the catalyst was filtered off and the filtrate was concentrated under vacuum to give an oily product in an amount of 16.47 g (yield: quantitative).

Workup

  1. customAfter the reaction
  2. filtrationthe catalyst was filtered off
  3. concentrationthe filtrate was concentrated under vacuum
  4. customto give an oily product in an amount of 16.47 g (yield: quantitative)

Sources & evidence

ORD record
ord-58a1a4e1132c4321a9e30f4f21356b86
Source dataset
uspto-grants-1985_12
Patent number
US04556735

Reaction notes

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