2-(3-Fluoro-4-nitrophenyl)propanoic acid → 2-(4-Amino-3-fluorophenyl)propanoic acid

Participants

Reaction Steps

In 100 ml of ethanol was dissolved 3 g of 2-(3-fluoro-4-nitrophenyl)propionic acid. To the solution was added 0.25 g of 5% palladium on charcoal to conduct catalytic hydrogenation. The catalyst was filtered off and the solvent was evaporated off under reduced pressure to afford 2.55 g of 2-(4-amino-3-fluorophenyl)propionic acid as an oily substance.

Provenance & Evidence