HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-dihydro-2,5-dimethyl-8-nitro-2H-1-benzopyran → 8-amino-3,4-dihydro-2,5-dimethyl-2H-1-benzopyran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-dihydro-2,5-dimethyl-8-nitro-2H-1-benzopyran | HCID 13560296 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 8-amino-3,4-dihydro-2,5-dimethyl-2H-1-benzopyran | HCID 13560297 | — |
Reaction Steps
A mixture of 27 g of 1D, 200 ml of THF and 2 g of activated Raney nickel catalyst was treated with hydrogen (40 psig) in a Parr shaker for 3 hours. The resulting mixture was dried (MgSO4), filtered and concentrated to dryness, to give 8-amino-3,4-dihydro-2,5-dimethyl-2H-1-benzopyran (1E), as an amber syrup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04558040 |
| Source dataset | uspto-grants-1985_12 |
| ORD ID | ord-2462054442c0426eb55e986976b6dd42 |
| Source note | uspto-grants-1985_12 |