Potassium Hydroxide → HCID 53854635, compound

HRID 637636Notes

Reaction equation

[C:1]([NH:11][C@H:12]([C:14]([N:16]([C:23]1[CH:27]=[CH:26][S:25][CH:24]=1)[CH2:17][C:18]([O:20]CC)=[O:19])=[O:15])[CH3:13])([O:3][CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:2].[OH-].[K+]>>[C:1]([NH:11][C@H:12]([C:14]([N:16]([C:23]1[CH:27]=[CH:26][S:25][CH:24]=1)[CH2:17][C:18]([OH:20])=[O:19])=[O:15])[CH3:13])([O:3][CH2:4][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1)=[O:2]

Participants

Reactant 2

HCID 14797Potassium Hydroxide

HCID 53923257HCID 53923257, compound

Product 1

HCID 53854635HCID 53854635, compound

Procedure

An ethanolic solution of ethyl N-carbobenzyloxy-L-alanyl-N-(3-thienyl)glycinate was treated with two equivalents of potassium hydroxide to yield N-carbobenzyloxy-L-alanyl-N-(3-thienyl)glycine.

Sources & evidence

ORD record: ord-810d56e336654b06a4944371fabd3603
Source dataset: uspto-grants-1985_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04558038

Reaction notes

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