Potassium Hydroxide → N-carbobenzyloxy-L-isoleucyl-N-(3-pyridyl)glycine

HRID 637639Notes

Reaction equation

HRID 637639 reaction equation
[C:1]([NH:11][C@H:12]([C:17]([N:19]([C:26]1[CH:27]=[N:28][CH:29]=[CH:30][CH:31]=1)[CH2:20][C:21]([O:23]CC)=[O:22])=[O:18])[C@H:13]([CH2:15][CH3:16])[CH3:14])([O:3][CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:2].[OH-].[K+]>>[C:1]([NH:11][C@H:12]([C:17]([N:19]([C:26]1[CH:27]=[N:28][CH:29]=[CH:30][CH:31]=1)[CH2:20][C:21]([OH:23])=[O:22])=[O:18])[C@H:13]([CH2:15][CH3:16])[CH3:14])([O:3][CH2:4][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1)=[O:2]

Participants

3

Reactant 2

HCID 14797Potassium HydroxideHCID 54257317Ethyl N-Carbobenzyloxy-L-isoleucyl-N-(3-pyridyl)glycinate

Product 1

HCID 54567953N-carbobenzyloxy-L-isoleucyl-N-(3-pyridyl)glycine

Procedure

An ethanolic solution of ethyl N-carbobenzyloxy-L-isoleucyl-N-(3-pyridyl)glycinate was treated with potassium hydroxide to yield N-carbobenzyloxy-L-isoleucyl-N-(3-pyridyl)glycine.

Sources & evidence

ORD record
ord-ba9186e227ab4216ad017f5ccc42cd3a
Source dataset
uspto-grants-1985_12
Patent number
US04558038

Reaction notes

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