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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 637701Generated: October 30, 2026

1-(2-Methoxyphenyl)piperazine → 2(3H)-Benzoxazolone, 6-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-3-methyl-

https://huagongshe.com/reaction/637701

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Methoxyphenyl)piperazineHCID 1346—
ReactantHCID 13306088HCID 13306088—
Product2(3H)-Benzoxazolone, 6-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-3-methyl-HCID 5643665.1%

Reaction Steps

By following the procedure indicated in Example 1, but starting from 5.12 g of 3-methyl-6-(2-bromoethyl)-benzoxazolinone and 4.82 g of 1-(2-methoxyphenyl)-piperazine, 4.78 g of the title product having a melting point of 137°-137.5° C. were obtained after crystallisation from cyclohexane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04558060
Source datasetuspto-grants-1985_12
ORD IDord-833d42e5f835483c8f0c544cd78356d8
Source noteuspto-grants-1985_12