Methylamine → 5-Thiazolecarboxamide, N,4-dimethyl-2-(4-methoxyphenyl)-

Participants

Reaction Steps

Into a mixed solvent of 80 ml of 40% methylamine and 600 ml of ethanol, 13.9 g of ethyl 2-(4-methoxyphenyl)-4-methylthiazole-5-carboxylate was dissolved. Then, in a similar manner as in Example 1, the object was obtained as colourless minute aciculate melting at 157.5° to 159° C. in an amount of 9.1 g corresponding to the yield of 69%.

Provenance & Evidence