Sodium Hydroxide → 3-Acetyl-2-[2-[3-(carboxy)propoxy]phenyl]benzothiazoline

Participants

Reaction Steps

To the solution of 7.71 g of 3-acetyl-2-[2-[3-(ethoxycarbonyl)propoxy]phenyl]benzothiazoline in 50 ml of methanol, 2N-sodium hydroxide solution is added and the reaction mixture is stirred for 2 hours at room temperature. Methanol is removed off in vacuo. The residue is acidified with 2N-hydrochloric acid to give 5.72 g (80%) of the titled compound.

Provenance & Evidence