HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichlorophenol → 2-(3,4-Dichlorophenoxy)-5-ethylthio-4-pyridinecarbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichlorophenol | HCID 7258 | — |
| Reactant | 2-Chloro-5-ethylthio-4-pyridinecarbonitrile | HCID 13560211 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(3,4-Dichlorophenoxy)-5-ethylthio-4-pyridinecarbonitrile | HCID 13560226 | — |
Reaction Steps
2-Chloro-5-ethylthio-4-pyridinecarbonitrile (4.0 g) was reacted with 3.6 g of 3,4-dichlorophenol in the presence of 2.6 g of t-BuOK in 40 ml of THF and 4 ml of DMSO. 5.5 g (84.6%) of the desired, 2-(3,4-dichlorophenoxy)-5-ethylthio-4-pyridinecarbonitrile was recovered, m.p. 68°-69° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04558134 |
| Source dataset | uspto-grants-1985_12 |
| ORD ID | ord-707a4ffc5d454e00833d5210d618aff8 |
| Source note | uspto-grants-1985_12 |