反应详情

A solution of 144.0 g (1 mole) α-naphthol and 56.1 g (1 mole) potassium hydroxide in 600 ml of 95% ethanol was stirred 1.5 hr at room temperature. To this solution of potassium naphthalate was added 930.0 g (5.0 mole) of 1,2-dibromoethane, and the solution was heated at reflux overnight. The reaction mixture was filtered, and the filtrate stripped to dryness under reduced pressure in a rotary evaporator. The resulting oil was dissolved in chloroform and the solution extracted with 10% aqueous sodium hydroxide. The chloroform layer was dried and stripped of chloroform to yield 126 g (50.3%) of dark brown oil.

1. temperaturethe solution was heated
2. temperatureat reflux overnight
3. filtrationThe reaction mixture was filtered
4. customthe filtrate stripped to dryness under reduced pressure in a rotary evaporator
5. dissolutionThe resulting oil was dissolved in chloroform
6. extractionthe solution extracted with 10% aqueous sodium hydroxide
7. dry with materialThe chloroform layer was dried