Isopropylamine → HCID 20256376, compound

HRID 637841Notes

Reaction equation

HRID 637841 reaction equation
BrCCC1C(Cl)=[C:6]([O:11][C:12]2[CH:17]=[C:16]([Cl:18])[CH:15]=[C:14](CCBr)[C:13]=2[Cl:22])[CH:7]=C([Cl:10])C=1.[CH:24]([NH2:27])([CH3:26])[CH3:25]>>[ClH:10].[Cl:22][C:13]1[CH:14]=[CH:15][C:16]([Cl:18])=[CH:17][C:12]=1[O:11][CH2:6][CH2:7][NH:27][CH:24]([CH3:26])[CH3:25]

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 86739922HCID 86739922, compound

Product 1

HCID 20256376HCID 20256376, compound

Procedure

Following the procedure of Preparation 11, 2-bromoethyl-2,5-dichlorophenyl ether and isopropyl amine (excess) were reacted and the reaction mixture processed to give an oil, the free base of the title compound. A portion of the oil was reacted with ethereal hydrogen chloride to give the hydrochloride salt, m.p. 152°-155° C. in 63.3% yield.

Workup

  1. customwere reacted
  2. customto give an oil

Sources & evidence

ORD record
ord-9bc01e9f60094a90ac0243cab74770ab
Source dataset
uspto-grants-1985_12
Patent number
US04558155

Reaction notes

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