反应详情

17.8 g (0.092 mole) of 3-(6-methyl-3-pyridyl)-acrylic acid ethyl ester in 100 ml of ethanol are hydrogenated at 40° C./atmospheric pressure in the presence of 1.0 g of palladium/active carbon (10% Pd). On completion of the reaction, the reaction mixture is filtered and the solvent is concentrated in vacuo, leaving 16.2 g (90%) of a colorless oil.

1. customare hydrogenated at 40° C.
2. customOn completion of the reaction
3. filtrationthe reaction mixture is filtered
4. concentrationthe solvent is concentrated in vacuo