HCID 10909621, compound → HCID 86740555, compound

HRID 637934Notes

Reaction equation

HRID 637934 reaction equation
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[N:5]=[C:4]([CH2:9][C:10]([O:12][CH2:13][CH3:14])=[S:11])[N:3]=1.[CH3:15][NH:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([CH3:23])[C:18]=1[CH3:24]>C(O)C>[Cl:8][C:6]1[CH:7]=[C:2]([N:16]([CH3:15])[C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([CH3:23])[C:18]=2[CH3:24])[N:3]=[C:4]([CH2:9][C:10]([O:12][CH2:13][CH3:14])=[S:11])[N:5]=1

Participants

4

Reactant 2

HCID 10909621HCID 10909621, compoundHCID 54036785HCID 54036785, compound

Product 1

HCID 86740555HCID 86740555, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a suspensione of ethyl 4,6-dichloro-2-pyrimidinylthioacetate (10.7 g) in ethanol (100 ml) anhydrous NaCO3 (4.66 g) and N-methyl-2,3-xylidine (6.2 g) are added; the mixture is refluxed under stirring for 24 hours.

Workup

  1. temperaturethe mixture is refluxed

Sources & evidence

ORD record
ord-88eed6b0e71c4a6a864565449fd95529
Source dataset
uspto-grants-1985_12
Patent number
US04559345

Reaction notes

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