HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethyl orthoformate → HCID 89501076, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethyl orthoformate | HCID 9005 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 4-Chloro-5-fluoro-2-iodoaniline | HCID 57538963 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 89501076 | HCID 89501076 | 872.9% |
Reaction Steps
To Intermediate 5A (47 g, 17.3 mmol) in AcOH (470 mL) was added NaN3 (33.76 g, 51.9 mmol) and trimethyl orthoformate (56.8 mL, 51.9 mmol). After 30 h, the reaction was poured into ice H2O, the solids were filtered-off and washed with petroleum ether to afford 49 g Intermediate 5B. MS (ESI) m/z: 324.8 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09447110B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-372afd687eeb435392ee0d4c8823bfb1 |
| Source note | uspto-grants-2016_09 |