Ammonium Acetate → HCID 10104952, compound

Participants

Reaction Steps

A mixture containing 13.4 g of 5-benzoyl-6-[2-(dimethylamino)ethenyl]-2(1H)-pyridinone, 100 ml of dimethylformamide and 12 g of ammonium acetate was heated with stirring on a steam bath for 7 hours and then concentrated on a rotary evaporator. The remaining solid residue was treated with 100 ml of water, the mixture filtered, the collected solid air-dried, recrystallized from ethanol and dried in a vacuum oven at 90°-95° C. to yield 6.3 g of 5-phenyl-1,6-naphthyridin-2(1H)-one, m.p. 261°-263° C.

Provenance & Evidence