HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → alpha-Ethyl-4-hydroxybenzeneacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 2-(4-Methoxyphenyl)butanoic acid | HCID 34657 | — |
| Product | alpha-Ethyl-4-hydroxybenzeneacetic acid | HCID 34656 | — |
Reaction Steps
The m- or p-hydroxyphenyl alkanol can also be prepared using conventional techniques. For example, a m- or p-methoxyphenylbutyric acid can be reacted at reflux temperature with hydrogen bromide to form a m- or p-hydroxyphenylbutyric acid. This acid can then be reacted with borane in tetrahydrofuran to form m- or p-hydroxyphenylbutanol. This latter compound is reported in JACS, 84, 788 (1962).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04560701 |
| Source dataset | uspto-grants-1985_12 |
| ORD ID | ord-11dd66ce274b4057ac104caf680782e2 |
| Source note | uspto-grants-1985_12 |