HCID 13603935, compound → HCID 13603936, compound

HRID 638275Notes

Reaction equation

HRID 638275 reaction equation
C([O:3][C:4]([CH:6]1[CH2:11][CH2:10][N:9]([C:12]2[C:21]3[C:16](=[CH:17][CH:18]=[C:19]([F:22])[CH:20]=3)[N:15]=[C:14]([C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[CH:13]=2)[CH2:8][CH2:7]1)=[O:5])C>[OH-].[Na+]>[F:22][C:19]1[CH:20]=[C:21]2[C:16](=[CH:17][CH:18]=1)[N:15]=[C:14]([C:23]1[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1)[CH:13]=[C:12]2[N:9]1[CH2:10][CH2:11][CH:6]([C:4]([OH:5])=[O:3])[CH2:7][CH2:8]1

Participants

3

Reactant 1

HCID 13603935HCID 13603935, compound

Product 1

HCID 13603936HCID 13603936, compoundYield 100.8%

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

From 6.0 g of 1-[6-fluoro-2-phenyl-4-quinolinyl]-4-piperidinecarboxylic acid ethyl ester and 10 ml of 3N sodium hydroxide, treated in a manner similar to that described in Example 1C, there was obtained 5.6 g of product as yellow needles, mp 255°-260° dec.

Sources & evidence

ORD record
ord-ce5f81de8f3d469b9aa2a428e207be33
Source dataset
uspto-grants-1985_12
Patent number
US04560692

Reaction notes

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