HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 13603937, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 13603936 | HCID 13603936 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 13603937 | HCID 13603937 | — |
Reaction Steps
A mixture of 4 g of 1-[6-fluoro-2-phenyl-4-quinolinyl]-4-piperidinecarboxylic acid, 12 ml of thionyl chloride, and 100 ml of methylene chloride were stirred and heated under reflux for 1 hr. The reaction mixture was cooled and concentrated in vacuo to leave 4.2 g of product as a yellow solid, mp 243°-5°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04560692 |
| Source dataset | uspto-grants-1985_12 |
| ORD ID | ord-54d4ede9d04c48abbb2e9baa7eab1a8b |
| Source note | uspto-grants-1985_12 |