Ethylamine → HCID 13603917, compound

HRID 638277Notes

Reaction equation

HRID 638277 reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH:6]=[C:5]2[N:18]1[CH2:23][CH2:22][CH:21]([C:24](Cl)=[O:25])[CH2:20][CH2:19]1.[CH2:27]([NH2:29])[CH3:28]>>[CH2:27]([NH:29][C:24]([CH:21]1[CH2:22][CH2:23][N:18]([C:5]2[C:4]3[C:9](=[CH:10][CH:11]=[C:2]([F:1])[CH:3]=3)[N:8]=[C:7]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[CH:6]=2)[CH2:19][CH2:20]1)=[O:25])[CH3:28]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 13603937HCID 13603937, compound

Product 1

HCID 13603917HCID 13603917, compound

Procedure

In a manner analogous to that of Example 1(e) but using 1-[(6-fluoro-2-phenyl-4-quinolinyl]-4-piperidinecarbonyl chloride and ethylamine as starting materials the named compound was obtained as cream-colored needles, mp 225°-227° dec after recrystallization from methanol.

Workup

  1. customwas obtained as cream-colored needles, mp 225°-227° dec
  2. customafter recrystallization from methanol

Sources & evidence

ORD record
ord-e151b31a2a2340c69c375056e73e209b
Source dataset
uspto-grants-1985_12
Patent number
US04560692

Reaction notes

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