4-Piperidinecarboxamide → HCID 13603922, compound

HRID 638282Notes

Reaction equation

HRID 638282 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:12]2[CH:17]=[CH:16][C:15]([CH3:18])=[CH:14][CH:13]=2)[CH:3]=1.[NH:19]1[CH2:27][CH2:26][CH:22]([C:23]([NH2:25])=[O:24])[CH2:21][CH2:20]1>>[CH3:18][C:15]1[CH:16]=[CH:17][C:12]([C:4]2[CH:3]=[C:2]([N:19]3[CH2:27][CH2:26][CH:22]([C:23]([NH2:25])=[O:24])[CH2:21][CH2:20]3)[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[N:5]=2)=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 37724-PiperidinecarboxamideHCID 11118595HCID 11118595, compound

Product 1

HCID 13603922HCID 13603922, compound

Procedure

In a manner analogous to that of Example 1(b), but using 4-chloro-2-(4-methylphenyl)quinoline and isonipecotamide as starting materials, the named product was produced, mp. 230°-232° on recrystallization from acetonitrile.

Workup

  1. customthe named product was produced
  2. custommp. 230°-232° on recrystallization from acetonitrile

Sources & evidence

ORD record
ord-2e05d809ef654cbb9d6216540645a462
Source dataset
uspto-grants-1985_12
Patent number
US04560692

Reaction notes

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