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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 638288Generated: October 26, 2026

N-methylpiperidine-4-carboxamide → 1-[6-Fluoro-2-(4-chlorophenyl)-4-quinolinyl]-N-methyl-4-piperidinecarboxamide

https://huagongshe.com/reaction/638288

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methylpiperidine-4-carboxamideHCID 2760460—
Reactant4-Chloro-2-(4-chlorophenyl)-6-fluoroquinolineHCID 13603895—
Product1-[6-Fluoro-2-(4-chlorophenyl)-4-quinolinyl]-N-methyl-4-piperidinecarboxamideHCID 20253658—

Reaction Steps

The named compound was made in a manner analogous to that of Example 4(c) using 4-chloro-2-(4-chlorophenyl)-6-fluoroquinoline, prepared as described in Example 4(b), and N-methylisonipecotamide as starting materials. It was obtained as colorless needles, mp 279°-282°dec on recrystallization from pyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04560692
Source datasetuspto-grants-1985_12
ORD IDord-628f7fed6f23474d894b2aaff018b534
Source noteuspto-grants-1985_12