反应详情

To a solution of 300 mg of 5-(4-vinylbenzoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid in pb 5 ml of methanol is added 1 molar equivalent of sodium hydroxide, in the form of a 0.1 N solution. The solvent is taken up in 2 ml of methanol, followed by precipitation with ether, to yield crude sodium 5-(4-vinylbenzoyl)-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylate which can be crystallized from ethyl acetate-hexane.

1. customfollowed by precipitation with ether