HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → Ethyl 4-[4-(6,7-dichloro-2-quinoxalyloxy)phenoxy]-3-methoxy-2-pentenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2,6,7-Trichloroquinoxaline | HCID 10036978 | — |
| Reactant | Ethyl 4-(4-hydroxyphenoxy)-3-methoxy-2-pentenoate | HCID 54412603 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | Ethyl 4-[4-(6,7-dichloro-2-quinoxalyloxy)phenoxy]-3-methoxy-2-pentenoate | HCID 54001181 | — |
Reaction Steps
A mixture of 2,6,7-trichloroquinoxaline (0.8 eq, 3.43 ml.), ethyl 4-(4-hydroxyphenoxy)-3-methoxy-2-pentenoate (1.09 g, 1.2 eq), K2CO3 (568 mg) and CH3CN (20 ml) is refluxed overnight and then filtered. The filtrate is concentrated and taken up in CH2Cl2. The CH2Cl2 solution is washed, dried and evaporated to dryness to yield crystalline enol ether, i.e., ethyl 4-[4-(6,7-dichloro-2-quinoxalyloxy)phenoxy]-3-methoxy-2-pentenoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04561882 |
| Source dataset | uspto-grants-1985_12 |
| ORD ID | ord-e987836e973e4866a2cb6229ae71811e |
| Source note | uspto-grants-1985_12 |