HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroquinone → Ethyl 4-(4-hydroxyphenoxy)-3-methoxy-2-pentenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroquinone | HCID 785 | — |
| Reactant | Ethyl 4-bromo-3-methoxypent-2-enoate | HCID 53787831 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | Ethyl 4-(4-hydroxyphenoxy)-3-methoxy-2-pentenoate | HCID 54412603 | — |
Reaction Steps
The above 3-oxo ester is reduced using NaBH4 in ethanol to yield ethyl 4-[4-(6,7-dichloro-2-quinoxalyloxy)phenoxy]-3-hydroxypentanoate. Ethyl 4-(4-hydroxyphenoxy)-3-methoxy-2-pentenoate is prepared by the reaction of hydroquinone and ethyl 4-bromo-3-methoxy-2-pentenoate in the presence of base in acetone or the like under reflux.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04561882 |
| Source dataset | uspto-grants-1985_12 |
| ORD ID | ord-e1f02ccdffd94ceb8c2ffdcb540d90f1 |
| Source note | uspto-grants-1985_12 |