HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → N-Methylcarbazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Carbazole | HCID 6854 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Methyl sulfate(1-) | HCID 4694097 | — |
| Product | N-Methylcarbazole | HCID 15142 | 90% |
Reaction Steps
To a vigourously stirred solution of 10 g of carbazole in 50 ml of acetone, 10 ml methyl sulphate was added, followed by dropwise addition of a solution of 10 g NaOH in 7 ml water. After a few minutes the solution was poured into water. N-methyl carbazole was purified by two ethanol recrystallization, extraction with boiling petroleum ether and another ethanol recrystallization (yield 90% m.p.=88° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04562133 |
| Source dataset | uspto-grants-1985_12 |
| ORD ID | ord-dbd95565ba8f41bfba74efab74af9a0c |
| Source note | uspto-grants-1985_12 |