反应详情

A 2.82 g (0.01 mole) amount of 3-amino-5-(4-benzyl-1-piperazinyl)-4-pyrazolecarbonitrile (prepared as described in Example 8) was added to 50 ml of acetic anhydride with stirring. After nearly complete solution a heavy precipitate was formed. The mixture was stirred for 18 hours at room temperature beneath a drying tube containing a desicant.

1. customAfter nearly complete solution a heavy precipitate was formed
2. stirringThe mixture was stirred for 18 hours at room temperature beneath a drying tube
3. additioncontaining a desicant