Iodoethane → HCID 20252626, compound

Participants

Reaction Steps

31.2 g (0.2 mole) of ethyl iodide are added to a solution of 6.2 g (0.02 mole) of 5-(3,4-dichlorophenyl)-5-aminocarbonyl-1,2,3-oxathiazolidin-4-one-2-oxide and 2.02 g (0.02 mole) of triethylamine in 50 ml of acetonitrile. The solution is heated to the boil for four hours and then evaporated down under reduced pressure. The residue is taken up in 50 ml of dichloromethane, and the solution is washed with three times 20 ml of water. The organic phase is evaporated down and the residue is triturated with diethyl ether. In this manner, 4.7 g (70% of theory) of 3-ethyl-5-(3,4-dichlorophenyl)-5-aminocarbonyl-1,2,3-oxathiazolidin-4-one-2-oxide of melting point 127°-128° C. are obtained.

Provenance & Evidence