Acetic Anhydride → Acetate

Participants

Reaction Steps

To a solution containing 2.8 g of 5-phenyltetrazolo[1,5-a][1,2,4]triazolo[1,5-c]pyrimidine-6-ethanol (0.01 mole) dissolved in 15 ml of pyridine is added 1.5 ml of acetic anhydride (0.015 mole). The reaction mixture is maintained at room temperature for 48 hours and then is evaporated to dryness yielding a crude product. The crude product is chromatographed on silica gel and recrystallized from diethyl ether to yield 5-phenyltetrazolo[1,5-a][1,2,4]triazolo[1,5-c]pyrimidine-6-ethanol, acetate (ester) having the structural formula ##STR23## and the azido tautomer thereof as a white solid having a melting point of 114° C. and the following elemental analysis:

Provenance & Evidence