Hydrochloric Acid → HCID 70411291, compound

Participants

Reaction Steps

A mixture of ethyl 3-[3-bromo-4-(imidazol-1-ylmethyl)phenyl]prop-2-enoate (0.12 g) in hydrochloric acid (2 ml, 6M) was stirred and heated under reflux for 2 h. The reaction mixture was concentrated under reduced pressure and toluene (5 ml) was added and the reaction mixture was again concentrated to give a white solid. Recrystallisation of the solid from ethanol/ether gave 3-[3-bromo-4-(imidazol-1-ylmethyl)phenyl]prop-2-enoic acid hydrochloride as a white solid, m.p. 247°-249°.

Provenance & Evidence