Diazomethane → HCID 56630801, compound

HRID 638633Notes

Reaction equation

HRID 638633 reaction equation
[CH2:1]([C@H:5]1[CH2:9][CH2:8][CH:7]([C:10]([OH:12])=[O:11])[CH2:6]1)[CH2:2][CH2:3][CH3:4].[N+](=[CH2:15])=[N-]>C(OCC)C>[CH3:15][O:11][C:10]([CH:7]1[CH2:8][CH2:9][C@H:5]([CH2:1][CH2:2][CH2:3][CH3:4])[CH2:6]1)=[O:12]

Participants

4

Reactant 2

HCID 9550DiazomethaneHCID 56617818HCID 56617818, compound

Product 1

HCID 56630801HCID 56630801, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A mixture of 84 mg of (1RS,3S)-3-butylcyclopentanecarboxylic acid (prepared in Reference Example 14) and 1.0 ml of a 1M solution of diazomethane in diethyl ether was stirred with cooling. The mixture was concentrated under ambient pressure to give 72 mg of the title compound having the following physical characteristic.

Workup

  1. temperaturewith cooling
  2. concentrationThe mixture was concentrated under ambient pressure

Sources & evidence

ORD record
ord-0dabe0c67bf842488c172bb533de33c0
Source dataset
uspto-grants-1985_12
Patent number
US04562207

Reaction notes

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