Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 6389Generated: October 29, 2026

1-Cyano-6-methoxy-2-phenylmethylcarbonyl-1,2,3,4-tetrahydronaphthalene → 2,3,3a,4,5,9b-Hexahydro-3-(3-methylphenyl)methyl-1H-benz[e]isoindole

https://huagongshe.com/reaction/6389

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Cyano-6-methoxy-2-phenylmethylcarbonyl-1,2,3,4-tetrahydronaphthaleneHCID 19793203—
Reactant1-Cyano-2-(3-methylphenyl)methylcarbonyl-1,2,3,4-tetrahydronaphthaleneHCID 19793260—
Product2,3,3a,4,5,9b-Hexahydro-3-(3-methylphenyl)methyl-1H-benz[e]isoindoleHCID 19793270—

Reaction Steps

Following the procedures described in Step 2 of Example 6, replacing 1-cyano-6-methoxy-2-phenylmethylcarbonyl-1,2,3,4-tetrahydronaphthalene (the product of Step 1 of Example 6) with the product of Step 1 above, 1-cyano-2-(3-methylphenyl)methylcarbonyl-1,2,3,4-tetrahydronaphthalene, the title compound was prepared; MS DCl--NH3M/Z: 278 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05248677
Source datasetuspto-grants-1993_09
ORD IDord-4393075ba1aa42428cf8d5fd71a2583e
Source noteuspto-grants-1993_09