Methyl iodide → 3,4-Dimethoxy-5-propylbenzoic acid methyl ester

HRID 638909Notes

Reaction equation

HRID 638909 reaction equation
[CH3:1][O:2][C:3](=[O:16])[C:4]1[CH:9]=[C:8]([CH2:10][CH2:11][CH3:12])[C:7]([OH:13])=[C:6]([O:14][CH3:15])[CH:5]=1.[CH3:17]I>>[CH3:1][O:2][C:3](=[O:16])[C:4]1[CH:9]=[C:8]([CH2:10][CH2:11][CH3:12])[C:7]([O:13][CH3:17])=[C:6]([O:14][CH3:15])[CH:5]=1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 68685299HCID 68685299, compound

Product 1

HCID 686849273,4-Dimethoxy-5-propylbenzoic acid methyl esterYield 99%

Procedure

3,4-Dimethoxy-5-propylbenzoic acid methyl ester was prepared from 4-hydroxy-3-methoxy-5-propylbenzoic acid methyl ester using methyl iodide as an alkylating agent in 99% yield by following Method C. The reaction was conducted at room temperature for 4 h, for complete conversion of starting material. The resulting product was used without further purification.

Workup

  1. customThe resulting product was used without further purification

Sources & evidence

ORD record
ord-edd61c66dce84aa99d93e64ec26912ec
Source dataset
uspto-grants-2010_04
Patent number
US07691843B2

Reaction notes

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