Allyl bromide → 3,4-Dimethoxy-5-{3-[(prop-2-en-1-yl)oxy]propyl}benzoic acid

HRID 638914Notes

Reaction equation

HRID 638914 reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][C:5]1[CH:6]=[C:7]([CH:11]=[C:12]([O:16][CH3:17])[C:13]=1[O:14][CH3:15])[C:8]([OH:10])=[O:9].[CH2:18](Br)[CH:19]=[CH2:20]>>[CH2:20]([O:1][CH2:2][CH2:3][CH2:4][C:5]1[CH:6]=[C:7]([CH:11]=[C:12]([O:16][CH3:17])[C:13]=1[O:14][CH3:15])[C:8]([OH:10])=[O:9])[CH:19]=[CH2:18]

Participants

3

Reactant 2

HCID 7841Allyl bromideHCID 686851493-(3-Hydroxypropyl)-4,5-dimethoxybenzoic acid

Product 1

HCID 686857723,4-Dimethoxy-5-{3-[(prop-2-en-1-yl)oxy]propyl}benzoic acid

Procedure

3-(3-Allyloxypropyl)-4,5-dimethoxybenzoic acid was prepared from 3-(3-hydroxypropyl)-4,5-dimethoxybenzoic acid (Example 10, Step 1) and allyl bromide in quantitative yield by following Method I and used without further purification.

Workup

  1. customused without further purification

Sources & evidence

ORD record
ord-5a4b7599dae44cc090ebd3ee46204518
Source dataset
uspto-grants-2010_04
Patent number
US07691843B2

Reaction notes

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