反应详情

Dissolve 1,1-dimethylethyl(3S,4S)-3-hydroxy-4-[({[(phenylmethyl)oxy]carbonyl}amino)methyl]-1-pyrrolidinecarboxylate (0.75 g, 2.14 mmol) in methanol (10 mL). Add 20% PdOH (catalytic) and subject to H at 55 PSI on a Parr hydrogenation apparatus. The solution was filtered through a plug of celite and concentrated under reduced pressure to yield an oil. (0.712 g, quantitative) LCMS: m/z 133.2 (MH+).

1. filtrationThe solution was filtered through a plug of celite
2. concentrationconcentrated under reduced pressure
3. customto yield an oil