Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Phenylpropylamine → 10-[(2,2'-Dimethyl-1,1'-biphenyl-4-YL)carbonyl]-N-(3-phenylpropyl)-10,11-dihydro-5H-pyrrolo[2,1-C][1,4]benzodiazepine-3-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Phenylpropylamine | HCID 16259 | — |
| 반응물 | 2,2,2-Trichloro-1-{10-[(2,2'-dimethyl-1,1'-biphenyl-4-yl)carbonyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-3-yl}ethanone | HCID 16038471 | — |
| 생성물 | 10-[(2,2'-Dimethyl-1,1'-biphenyl-4-YL)carbonyl]-N-(3-phenylpropyl)-10,11-dihydro-5H-pyrrolo[2,1-C][1,4]benzodiazepine-3-carboxamide | HCID 16038677 | — |
반응 단계
The title compound was synthesized in the manner of Example 13 from 2,2,2-trichloro-1-{10-[(2,2′-dimethyl-1,1′-biphenyl-4-yl)carbonyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-3-yl}ethanone of Example 6 and 3-phenyl-1-propylamine, m.p. 183-184° C. MS [(+)ESI, m/z]: 554 [M+H]+ Anal. Calcd for C37H35N3O2: C, 80.26; H, 6.37; N, 7.59. Found: C, 80.18; H, 6.37; N, 7.51.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07691848B2 |
| 출처 데이터셋 | uspto-grants-2010_04 |
| ORD ID | ord-49d888bd656741c2a77751f27bd18f15 |
| 출처 메모 | uspto-grants-2010_04 |