2,4-Dimethylbenzylamine → N-(2,4-Dimethylbenzyl)-10-[(2-methoxy-2'-methyl-1,1'-biphenyl-4-YL)carbonyl]-10,11-dihydro-5H-pyrrolo[2,1-C][1,4]benzodiazepine-3-carboxamide

関与物質

反応手順

The title compound was prepared in the manner of Example 36 from 2,2,2-trichloro-1-{10-[(2-methoxy-2′-methyl-1,1′-biphenyl-4-yl)carbonyl]-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-3-yl}ethanone of Example 35 and 2,4-dimethyl benzylamine, m.p. 161-162° C. MS [(+)ESI, m/z]: 570 [M+H]+ Anal. Calcd for C37H35N3O3: C, 78.01; H, 6.19; N, 7.38. Found: C, 77.86; H, 6.40; N, 7.20.

情報源と証拠